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Histamine can be Formed and Degraded in the Human and Mouse Heart

Histamine is metabolized by several enzymes in vitro and in vivo. The relevance of this metabolism in the mammalian heart in vivo is unclear. However, histamine can exert positive inotropic effects (PIE) and positive chronotropic effects (PCE) in humans via H2-histamine receptors. In transgenic mice...

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Main Authors: Joachim Neumann (Author), Juliane M. Grobe (Author), Jacqueline Weisgut (Author), Hubert G. Schwelberger (Author), Wieslawa Agnieszka Fogel (Author), Margaréta Marušáková (Author), Hartmut Wache (Author), Heike Bähre (Author), Igor B. Buchwalow (Author), Stefan Dhein (Author), Britt Hofmann (Author), Uwe Kirchhefer (Author), Ulrich Gergs (Author)
Format: Book
Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
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