Single-cell transcriptome analysis reveals the regulatory effects of artesunate on splenic immune cells in polymicrobial sepsis

• Main Authors: Jiayun Chen (Author), Xueling He (Author), Yunmeng Bai (Author), Jing Liu (Author), Yin Kwan Wong (Author), Lulin Xie (Author), Qian Zhang (Author), Piao Luo (Author), Peng Gao (Author), Liwei Gu (Author), Qiuyan Guo (Author), Guangqing Cheng (Author), Chen Wang (Author), Jigang Wang (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis is characterized by a severe and life-threatening host immune response to polymicrobial infection accompanied by organ dysfunction. Studies on the therapeutic effect and mechanism of immunomodulatory drugs on the sepsis-induced hyperinflammatory or immunosuppression states of various immune c...