Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery.

Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery.

BACKGROUND:Chagas disease is a neglected tropical disease (NTD) caused by the eukaryotic parasite Trypanosoma cruzi. The current clinical and preclinical pipeline for T. cruzi is extremely sparse and lacks drug target diversity. METHODOLOGY/PRINCIPAL FINDINGS:In the present study we developed a comp...

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Main Authors: Sean Ekins (Author), Jair Lage de Siqueira-Neto (Author), Laura-Isobel McCall (Author), Malabika Sarker (Author), Maneesh Yadav (Author), Elizabeth L Ponder (Author), E Adam Kallel (Author), Danielle Kellar (Author), Steven Chen (Author), Michelle Arkin (Author), Barry A Bunin (Author), James H McKerrow (Author), Carolyn Talcott (Author)
Format: Book
Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
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