Metformin exhibits preventive and therapeutic efficacy against experimental cystic echinococcosis.

• Main Authors: Julia A Loos (Author), Valeria A Dávila (Author), Christian R Rodrígues (Author), Romina Petrigh (Author), Jorge A Zoppi (Author), Fernando A Crocenzi (Author), Andrea C Cumino (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metformin (Met) is an anti-hyperglycemic and potential anti-cancer agent which may exert its anti-proliferative effects via the induction of energetic stress. In this study we investigated the in vitro and in vivo efficacy of Met against the larval stage of Echinococcus granulosus. Metformin showed...