UCP2 Modulates Cardioprotective Effects of Ru360 in Isolated Cardiomyocytes during Ischemia

• मुख्य लेखकों: Lukas J. Motloch (लेखक), Sara Reda (लेखक), Martin Wolny (लेखक), Uta C. Hoppe (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2015-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Ruthenium 360 (Ru360) has been shown to induce cardioprotective mechanisms in perfused hearts. The agent is a specific blocker of the main cardiac mitochondrial uptake mechanism, the mitochondrial calcium uniporter (MCU). UCP2, a mitochondrial membrane protein, which influences cardiac...