Pharmacokinetics, pharmacodynamics, and exposure-efficacy of dupilumab in adults with atopic dermatitis

• Main Authors: Mohamed A. Kamal (Author), John D. Davis (Author), Pavel Kovalenko (Author), Kamal Srinivasan (Author), Eric L. Simpson (Author), Takeshi Nakahara (Author), Makoto Sugaya (Author), Atsuyuki Igarashi (Author), Marius Ardeleanu (Author), Christine Xu (Author), Kazuhiko Arima (Author)
• Format: Book
• Published: Wiley, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The pharmacokinetics (PKs) and exposure-efficacy of dupilumab have not been fully described for adults with atopic dermatitis (AD). Our objectives were to analyze the PKs and exposure-efficacy of dupilumab in adults with AD and compare the results of Japanese and overall populations. Adults...