Guanidines: Synthesis of Novel Histamine H<sub>3</sub>R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect

This study examines the properties of novel guanidines, designed and synthesized as histamine H<sub>3</sub>R antagonists/inverse agonists with additional pharmacological targets. We evaluated their potential against two targets viz., inhibition of MDA-MB-231, and MCF-7 breast cancer cell...

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Main Authors: Marek Staszewski (Author), Magdalena Iwan (Author), Tobias Werner (Author), Marek Bajda (Author), Justyna Godyń (Author), Gniewomir Latacz (Author), Agnieszka Korga-Plewko (Author), Joanna Kubik (Author), Natalia Szałaj (Author), Holger Stark (Author), Barbara Malawska (Author), Anna Więckowska (Author), Krzysztof Walczyński (Author)
Format: Book
Published: MDPI AG, 2023-04-01T00:00:00Z.
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