Inhibition by 2-Methoxy-4-ethylphenol of Ca2+ Influx Through Acquired and Native N-Methyl-d-aspartate-Receptor Channels

• Main Authors: Ryo Fukumori (Author), Noritaka Nakamichi (Author), Takeshi Takarada (Author), Yuki Kambe (Author), Nobuyuki Matsushima (Author), Nobuaki Moriguchi (Author), Yukio Yoneda (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pharmacological properties were evaluated for the antidiarrheic wood creosote ingredient 2-methoxy-4-ethylphenol (2M4EP), which was shown to be protective against neurotoxicity of N-methyl-d-aspartate (NMDA), to modulate Ca2+ influx across acquired and native NMDA receptor (NMDAR) channels. NMDA mar...