Brevilin A Ameliorates Acute Lung Injury and Inflammation Through Inhibition of NF-κB Signaling via Targeting IKKα/β

• Main Authors: Lu Liu (Author), Xian Chen (Author), Yifang Jiang (Author), Yun Yuan (Author), Luyao Yang (Author), Qiongying Hu (Author), Jianyuan Tang (Author), Xianli Meng (Author), Chunguang Xie (Author), Xiaofei Shen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) is life-threatening disease characterized by uncontrolled inflammatory response. IKKα/β, the key kinases in the activation of NF-κB pathway, are implicated in inflammatory pulmonary injury, and represent attractive targets for ALI therapy. Brevilin A (BVA) is a sesquiterpene...