ADAM17-Mediated Shedding of Inflammatory Cytokines in Hypertension
The increase of Angiontesin-II (Ang-II), one of the key peptides of the renin-angiotensin system (RAS), and its binding to the Ang-II type 1 receptor (AT1R) during hypertension is a crucial mechanism leading to AD\AM17 activation. Among the reported membrane anchored proteins cleaved by ADAM17, immu...
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Frontiers Media S.A.,
2020-07-01T00:00:00Z.
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