Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline-Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors
A series of quinoline-uracil hybrids (<b>10a-l</b>) has been rationalized and synthesized. The inhibitory activity against hCA isoforms I, II, IX, and XII was explored. Compounds <b>10a-l</b> demonstrated powerful inhibitory activity against all tested hCA isoforms. Compound...
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| Main Authors: | , , , , |
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| Format: | Book |
| Published: |
MDPI AG,
2022-04-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |