Methyleugenol Has an Antidepressant Effect in a Neuroendocrine Model: In Silico and In Vivo Evidence

• Main Authors: Mayara Cecile Nascimento Oliveira (Author), Ikla Lima Cavalcante (Author), Alana Natalícia de Araújo (Author), Aline Matilde Ferreira dos Santos (Author), Renata Priscila Barros de Menezes (Author), Chonny Herrera-Acevedo (Author), Natália Ferreira de Sousa (Author), Jailane de Souza Aquino (Author), José Maria Barbosa-Filho (Author), Ricardo Dias de Castro (Author), Reinaldo Nóbrega Almeida (Author), Luciana Scotti (Author), Marcus Tullius Scotti (Author), Mirian Graciela Da Silva Stiebbe Salvadori (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Major depressive disorder is a severe mood disorder characterized by different emotions and feelings. This study investigated the antidepressant activity of the phenylpropanoid methyleugenol (ME) in adult female mice exposed to a stress model induced by dexamethasone. The animals were randomly divid...