<i>Aconitum</i> Alkaloid Songorine Exerts Potent Gamma-Aminobutyric Acid-A Receptor Agonist Action In Vivo and Effectively Decreases Anxiety without Adverse Sedative or Psychomotor Effects in the Rat

• Main Authors: Zsolt Kristóf Bali (Author), Nóra Bruszt (Author), Zsombor Kőszegi (Author), Lili Veronika Nagy (Author), Tamás Atlasz (Author), Péter Kovács (Author), Dezső Csupor (Author), Boglárka Csupor-Löffler (Author), István Hernádi (Author)
• Format: Book
• Published: MDPI AG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Songorine (SON) is a diterpenoid alkaloid from <i>Aconitum</i> plants. Preparations of Aconitum roots have been employed in traditional oriental herbal medicine, however, their mechanisms of action are still unclear. Since GABA-receptors are possible brain targets of SON, we investigated...