Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions

• Main Authors: Xu Zheng (Author), Ke Wang (Author), Lang Pan (Author), Wenjing Hao (Author), Yaoyao Xue (Author), Attila Bacsi (Author), Spiros A. Vlahopoulos (Author), Zsolt Radak (Author), Tapas K. Hazra (Author), Allan R. Brasier (Author), Lloyd Tanner (Author), Xueqing Ba (Author), Istvan Boldogh (Author)
• Format: Book
• Published: Karger Publishers, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The primary cause of morbidity and mortality from infection with respiratory syncytial virus (RSV) is the excessive innate immune response(s) (IIR) in which reactive oxygen species (ROS) play key role(s). However, the mechanisms for these processes are not fully understood. We hypothesized that expr...