Elucidating the role of 4-hydroxy-2(3H)-benzoxazolone in chronic alcoholic liver disease via transcriptomics and metabolomics

• Main Authors: Jun-Fei Lu (Author), Shang-Ping Xing (Author), Xia Wei (Author), Chun-Xia Yang (Author), Gen-Shi Zhao (Author), Xiao-Lin Ma (Author), Xue-Mei Sun (Author), Hong-Wei Guo (Author), Zhi-Heng Su (Author), Bin Fang (Author), Jun Lin (Author), Yan-Ying Liu (Author), Dan Zhu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundChronic alcoholic liver disease (CALD) is a global health problem which includes multiple pathological processes such as immune inflammation and oxidative stress. 4-hydroxy-2(3H)-benzoxazolone (HBOA), an alkaloid isolated from Acanthus ilicifolius L, has been shown to exert hepatoprotectiv...