Elucidating the role of 4-hydroxy-2(3H)-benzoxazolone in chronic alcoholic liver disease via transcriptomics and metabolomics

• Главные авторы: Jun-Fei Lu (Автор), Shang-Ping Xing (Автор), Xia Wei (Автор), Chun-Xia Yang (Автор), Gen-Shi Zhao (Автор), Xiao-Lin Ma (Автор), Xue-Mei Sun (Автор), Hong-Wei Guo (Автор), Zhi-Heng Su (Автор), Bin Fang (Автор), Jun Lin (Автор), Yan-Ying Liu (Автор), Dan Zhu (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

BackgroundChronic alcoholic liver disease (CALD) is a global health problem which includes multiple pathological processes such as immune inflammation and oxidative stress. 4-hydroxy-2(3H)-benzoxazolone (HBOA), an alkaloid isolated from Acanthus ilicifolius L, has been shown to exert hepatoprotectiv...