Rapid diagnosis of spinal muscular atrophy using High-Resolution Melting Analysis

• Main Authors: Murong Shen (Author), Lin Min (Author), Lin Xiao (Author), Dong Wan (Author), Chen Wan (Author), Wu Zhi (Author), Wang Ning (Author)
• Format: Book
• Published: BMC, 2009-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Spinal muscular atrophy (SMA) is an autosomal recessive hereditary disorder caused by mutations of the survival motor neuron 1 (<it>SMN1</it>) gene. Recently, high-resolution DNA melting analysis (HRMA) with saturation LC...