Polymer-Surfactant System Based Amorphous Solid Dispersion: Precipitation Inhibition and Bioavailability Enhancement of Itraconazole

The rapid release of poorly water-soluble drugs from amorphous solid dispersion (ASD) is often associated with the generation of supersaturated solution, which provides a strong driving force for precipitation and results in reduced absorption. Precipitation inhibitors, such as polymers and surfacta...

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Bibliographic Details
Main Authors: Disang Feng (Author), Tingting Peng (Author), Zhengwei Huang (Author), Vikramjeet Singh (Author), Yin Shi (Author), Ting Wen (Author), Ming Lu (Author), Guilan Quan (Author), Xin Pan (Author), Chuanbin Wu (Author)
Format: Book
Published: MDPI AG, 2018-04-01T00:00:00Z.
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