Nose-to-brain delivery of borneol modified tanshinone IIA nanoparticles in prevention of cerebral ischemia/reperfusion injury

• Hlavní autoři: Luting Wang (Autor), Lin Xu (Autor), Junfeng Du (Autor), Xiao Zhao (Autor), Mei Liu (Autor), Jianfang Feng (Autor), Kaili Hu (Autor)
• Médium: Kniha
• Vydáno: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Targeted treatment of cerebral ischemia/reperfusion injury (CIRI) remains a problem due to the difficulty in drug delivery across the blood-brain barrier (BBB). In this study, we developed Bo-TSA-NP, a novel tanshinone IIA (TSA) loaded nanoparticles modified by borneol, which has long been proved wi...