Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c

• Main Authors: Fangshu Wu (Author), Junsheng Zhu (Author), Honglin Li (Author), Lili Zhu (Author)
• 格式: 图书
• 出版: Elsevier, 2017-05-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

UbcH5c belongs to the ubiquitin-conjugating enzyme family and plays an important role in catalyzing ubiquitination during TNF-α--triggered NF-κB activation. Therefore, UbcH5c is a potent therapeutic target for the treatment of inflammatory and autoimmune diseases induced by aberrant activation of NF...