Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c

UbcH5c belongs to the ubiquitin-conjugating enzyme family and plays an important role in catalyzing ubiquitination during TNF-α--triggered NF-κB activation. Therefore, UbcH5c is a potent therapeutic target for the treatment of inflammatory and autoimmune diseases induced by aberrant activation of NF...

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Main Authors: Fangshu Wu (Author), Junsheng Zhu (Author), Honglin Li (Author), Lili Zhu (Author)
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出版: Elsevier, 2017-05-01T00:00:00Z.
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索引号: A1234.567
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