4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-<i>β</i>-Lactamases

4-Amino-1,2,4-triazole-3-thione as a Promising Scaffold for the Inhibition of Serine and Metallo-<i>β</i>-Lactamases

The emergence of bacteria that co-express serine- and metallo- carbapenemases is a threat to the efficacy of the available <i>β</i>-lactam antibiotic armamentarium. The 4-amino-1,2,4-triazole-3-thione scaffold has been selected as the starting chemical moiety in the design of a small lib...

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Main Authors: Pasquale Linciano (Author), Eleonora Gianquinto (Author), Martina Montanari (Author), Lorenzo Maso (Author), Pierangelo Bellio (Author), Esmeralda Cebrián-Sastre (Author), Giuseppe Celenza (Author), Jesús Blázquez (Author), Laura Cendron (Author), Francesca Spyrakis (Author), Donatella Tondi (Author)
Format: Book
Published: MDPI AG, 2020-03-01T00:00:00Z.
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3rd Floor Main Library

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