Influence of <i>ABCB1</i> <i>3435C>T</i> polymorphism on methotrexate safety in patients with psoriasis

• Hauptverfasser: Alexey A. Kubanov (Verfasst von), Anastasiia V. Asoskova (Verfasst von), Michael S. Zastrozhin (Verfasst von), Zhannet A. Sozaeva (Verfasst von), Dmitry A. Sychev (Verfasst von)
• Format: Buch
• Veröffentlicht: State Scientific Center of Dermatovenereology and Cosmetology, 2023-02-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Background. Methotrexate is a highly effective systemic treatment for moderate to severe psoriasis, but drug toxicity may limit its use. Recent evidence suggests that it is necessary to take into account the individual characteristics of methotrexate pharmacokinetics, which are determined by the pre...