Therapeutic Angiogenesis by a "Dynamic Duo": Simultaneous Expression of HGF and VEGF165 by Novel Bicistronic Plasmid Restores Blood Flow in Ischemic Skeletal Muscle

• Hlavní autoři: Ekaterina Slobodkina (Autor), Maria Boldyreva (Autor), Maxim Karagyaur (Autor), Roman Eremichev (Autor), Natalia Alexandrushkina (Autor), Vadim Balabanyan (Autor), Zhanna Akopyan (Autor), Yelena Parfyonova (Autor), Vsevolod Tkachuk (Autor), Pavel Makarevich (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2020-12-01T00:00:00Z.
• Témata: article
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Therapeutic angiogenesis is a promising strategy for relief of ischemic conditions, and gene delivery was used to stimulate blood vessels' formation and growth. We have previously shown that intramuscular injection of a mixture containing plasmids encoding vascular endothelial growth factor (VE...