Evidence of Strong Guest-Host Interactions in Simvastatin Loaded in Mesoporous Silica MCM-41

• Main Authors: Teresa Cordeiro (Author), Inês Matos (Author), Florence Danède (Author), João C. Sotomayor (Author), Isabel M. Fonseca (Author), Marta C. Corvo (Author), Madalena Dionísio (Author), María Teresa Viciosa (Author), Frédéric Affouard (Author), Natália T. Correia (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A rational design of drug delivery systems requires in-depth knowledge not only of the drug itself, in terms of physical state and molecular mobility, but also of how it is distributed among a carrier and its interactions with the host matrix. In this context, this work reports the behavior of simva...