An inactivated recombinant rabies virus displaying the Zika virus prM-E induces protective immunity against both pathogens.

• Main Authors: Hongli Jin (Author), Cuicui Jiao (Author), Zengguo Cao (Author), Pei Huang (Author), Hang Chi (Author), Yujie Bai (Author), Di Liu (Author), Jianzhong Wang (Author), Na Feng (Author), Nan Li (Author), Yongkun Zhao (Author), Tiecheng Wang (Author), Yuwei Gao (Author), Songtao Yang (Author), Xianzhu Xia (Author), Hualei Wang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The global spread of Zika virus (ZIKV), which caused a pandemic associated with Congenital Zika Syndrome and neuropathology in newborns and adults, prompted the pursuit of a safe and effective vaccine. Here, three kinds of recombinant rabies virus (RABV) encoding the prM-E protein of ZIKV were const...