Acetylcholine protects mesenteric arteries against hypoxia/reoxygenation injury via inhibiting calcium-sensing receptor

• Main Authors: Ming Zhao (Author), Xi He (Author), Yong-Hua Yang (Author), Xiao-Jiang Yu (Author), Xue-Yuan Bi (Author), Yang Yang (Author), Man Xu (Author), Xing-Zhu Lu (Author), Qiang Sun (Author), Wei-Jin Zang (Author)
• Format: Book
• Published: Elsevier, 2015-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Ca2+-sensing receptor (CaSR) plays an important role in regulating vascular tone. In the present study, we investigated the positive effects of the vagal neurotransmitter acetylcholine by suppressing CaSR activation in mesenteric arteries exposed to hypoxia/reoxygenation (H/R). The artery rings...