Association between HLA-E gene polymorphism and unexplained recurrent spontaneous abortion (RSA) in Iranian women

• Main Authors: Maryam Fotoohi (Author), Nasrin Ghasemi (Author), Seyed Ali Mirghanizadeh (Author), Mahmood Vakili (Author), Morteza Samadi (Author)
• Format: Book
• Published: Shahid Sadoughi University of Medical Science, Yazd, Iran, 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Human leukocyte antigen-E (HLA-E)is a non-classical major histocompatibility complex (MHC) class I antigens which expressed on extra villous cytotrophoblast, which interacts with NKG2A, is an inhibitory receptor on natural killer (NK) cells and leading to down regulation of immune respon...