Identification of Glycyrrhiza as the rikkunshito constituent with the highest antagonistic potential on heterologously expressed 5HT3A receptors due to the action of flavonoids
The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT3 receptor antagonism, due to the involvement of these receptors in such pathophysiological processes. E.g. setrons, spec...
Saved in:
Main Authors: | Robin eHerbrechter (Author), Paul M Ziemba (Author), Katrin M Hoffmann (Author), Hanns eHatt (Author), Markus eWerner (Author), Guenter eGisselmann (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2015-07-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Kampo medicine: Evaluation of the pharmacological activity of 121 herbal drugs on GABA(A) and 5 HT3A receptors
by: Katrin M Hoffmann, et al.
Published: (2016) -
2-Aminoethoxydiphenyl borate activates the human mechano-gated KCNK channels KCNK 2 (TREK-1), KCNK 4 (TRAAK) and KCNK 10 (TREK-2).
by: Leopoldo Raul Beltran, et al.
Published: (2013) -
Identification of amino acids involved in histamine potentiation of GABA(A) receptors
by: Ulrike eThiel, et al.
Published: (2015) -
The pungent substances piperine, capsaicin, 6-gingerol and polygodial inhibit the human two-pore domain potassium channels TASK-1, TASK-3 and TRESK
by: Leopoldo Raul Beltran, et al.
Published: (2013) -
Rikkunshito, a ghrelin potentiator, ameliorates anorexia-cachexia syndrome
by: Naoki eFujitsuka, et al.
Published: (2014)