Glomerular capillary C3 deposition as a risk factor for unfavorable renal outcome in pediatric primary focal segmental glomerular sclerosis

• Main Authors: Yingchao Peng (Author), Banghai Li (Author), Xiaojie Li (Author), Tao Ju (Author), Zhiqiang Zhang (Author), Peipei Wang (Author), Tao Sun (Author), Jiaping Shu (Author), Meiqiu Wang (Author), Xiaoyi Sun (Author), Huangyu Chen (Author), Chunlin Gao (Author), Zhengkun Xia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionSome patients with primary focal segmental sclerosis (FSGS) demonstrate complement 3 (C3) deposition in glomerular capillary loops (Cap-C3) and/or mesangial area (Mes-C3). The clinicopathological and prognostic significance of C3 deposition remains incompletely investigated, especially i...