Chymase Dependent Pathway of Angiotensin II Generation and Rapeseed Derived Peptides for Antihypertensive Treatment of Spontaneously Hypertensive Rats

• Main Authors: Iwona Baranowska (Author), Olga Gawrys (Author), Malwina M. Roszkowska-Chojecka (Author), Bozena Badzynska (Author), Dagmara Tymecka (Author), Krzysztof H. Olszynski (Author), Elzbieta Kompanowska-Jezierska (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The contribution of chymase, one of the enzymes responsible for angiotensin II generation in non-ACE pathway, remains unclear in the development of hypertension. The aim of the study was to investigate chymase inhibition as potential antihypertensive therapy in spontaneously hypertensive rats (SHR)....