Natural compound Alternol actives multiple endoplasmic reticulum stress-responding pathways contributing to cell death

• Main Authors: Wang Liu (Author), Chenchen He (Author), Changlin Li (Author), Shazhou Ye (Author), Jiang Zhao (Author), Cunle Zhu (Author), Xiangwei Wang (Author), Qi Ma (Author), Benyi Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Alternol is a small molecular compound isolated from the fermentation of a mutant fungus obtained from Taxus brevifolia bark. Our previous studies showed that Alternol treatment induced reactive oxygen species (ROS)-dependent immunogenic cell death. This study conducted a comprehensive i...