Peroxisome Proliferator-Activated Receptor α Reduces Endothelin-1-Caused Cardiomyocyte Hypertrophy by Inhibiting Nuclear Factor-κB and Adiponectin

• Autores principales: Hsu-Lung Jen (Autor), Po-Len Liu (Autor), Yung-Hsiang Chen (Autor), Wei-Hsian Yin (Autor), Jaw-Wen Chen (Autor), Shing-Jong Lin (Autor)
• Formato: Libro
• Publicado: Hindawi Limited, 2016-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Peroxisome proliferator-activated receptor α (PPARα) plays a role in the pathogenesis of cardiac hypertrophy, although its underlying mechanism remains unclear. The purpose of this study was to evaluate the effect of PPARα activation on endothelin-1- (ET-1-) caused cardiomyocyte hypertrophy and expl...