Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism

• Hauptverfasser: Karissa Barthelson (Verfasst von), Morgan Newman (Verfasst von), Michael Lardelli (Verfasst von)
• Format: Buch
• Veröffentlicht: The Company of Biologists, 2022-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Energy production is the most fundamentally important cellular activity supporting all other functions, particularly in highly active organs, such as brains. Here, we summarise transcriptome analyses of young adult (pre-disease) brains from a collection of 11 early-onset familial Alzheimer's di...