Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.

• Main Authors: Alessandra Guidi (Author), Cristiana Lalli (Author), Roberto Gimmelli (Author), Emanuela Nizi (Author), Matteo Andreini (Author), Nadia Gennari (Author), Fulvio Saccoccia (Author), Steven Harper (Author), Alberto Bresciani (Author), Giovina Ruberti (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schistosomiasis, one of the most prevalent neglected parasitic diseases affecting humans and animals, is caused by the Platyhelminthes of the genus Schistosoma. Schistosomes are the only trematodes to have evolved sexual dimorphism and the constant pairing with a male is essential for the sexual mat...