Hypothalamic POMC deficiency increases circulating adiponectin despite obesity

• 主要な著者: Hui Yu (著者), Kavaljit H. Chhabra (著者), Zoe Thompson (著者), Graham L. Jones (著者), Sylee Kiran (著者), Gary Shangguan (著者), Malcolm J. Low (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2020-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Objective: The steep rise in the prevalence of obesity and its related metabolic syndrome have become a major worldwide health concerns. Melanocortin peptides from hypothalamic arcuate nucleus (Arc) POMC neurons induce satiety to limit food intake. Consequently, Arc Pomc-deficient mice (ArcPomc−/−)...