Individualized antibiotic dosage regimens for patients with augmented renal clearance

• Main Authors: A-Xi Shi (Author), Qiang Qu (Author), Hai-Hui Zhuang (Author), Xin-Qi Teng (Author), Wei-Xin Xu (Author), Yi-Ping Liu (Author), Yi-Wen Xiao (Author), Jian Qu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Augmented renal clearance (ARC) is a state of enhanced renal function commonly observed in 30%-65% of critically ill patients despite normal serum creatinine levels. Using unadjusted standard dosing regimens of renally eliminated drugs in ARC patients often leads to subtherapeutic concen...