Klotho Inhibits Unilateral Ureteral Obstruction-Induced Endothelial-to-Mesenchymal Transition via TGF-β1/Smad2/Snail1 Signaling in Mice

This study aimed to evaluate repression of Klotho on unilateral ureteral obstruction (UUO)-induced renal fibrosis and endothelial-to-mesenchymal transition (EndoMT) in mice. Renal fibrosis model was established by UUO in C57BL/6 male mice. Recombinant Klotho protein was administered to UUO mice as t...

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Main Authors: Shasha Li (Author), Lixia Yu (Author), Aolin He (Author), Qifeng Liu (Author)
Format: Book
Published: Frontiers Media S.A., 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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