Early Stage Preclinical Formulation Strategies to Alter the Pharmacokinetic Profile of Two Small Molecule Therapeutics

• Asıl Yazarlar: Le An (Yazar), Tom De Bruyn (Yazar), Jodie Pang (Yazar), Savita Ubhayakar (Yazar), Laurent Salphati (Yazar), Xing Zhang (Yazar), Liling Liu (Yazar), Ruina Li (Yazar), Bryan Chan (Yazar), Anwesha Dey (Yazar), Elizabeth S. Levy (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2024-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Early stage chemical development presents numerous challenges, and achieving a functional balance is a major hurdle, with many early compounds not meeting the clinical requirements for advancement benchmarks due to issues like poor oral bioavailability. There is a need to develop strategies for achi...