DNA Minicircle Technology Improves Purity of Adeno-associated Viral Vector Preparations

• Main Authors: Maria Schnödt (Author), Marco Schmeer (Author), Barbara Kracher (Author), Christa Krüsemann (Author), Laura Escalona Espinosa (Author), Anja Grünert (Author), Thomas Fuchsluger (Author), Anja Rischmüller (Author), Martin Schleef (Author), Hildegard Büning (Author)
• Format: Book
• Published: Elsevier, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adeno-associated viral (AAV) vectors are considered as one of the most promising delivery systems in human gene therapy. In addition, AAV vectors are frequently applied tools in preclinical and basic research. Despite this success, manufacturing pure AAV vector preparations remains a difficult task....