Search for Novel Potent Inhibitors of the SARS-CoV-2 Papain-like Enzyme: A Computational Biochemistry Approach

• Main Authors: Manuel I. Osorio (Author), Osvaldo Yáñez (Author), Mauricio Gallardo (Author), Matías Zuñiga-Bustos (Author), Jorge Mulia-Rodríguez (Author), Roberto López-Rendón (Author), Olimpo García-Beltrán (Author), Fernando González-Nilo (Author), José M. Pérez-Donoso (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The rapid emergence and spread of new variants of coronavirus type 2, as well as the emergence of zoonotic viruses, highlights the need for methodologies that contribute to the search for new pharmacological treatments. In the present work, we searched for new SARS-CoV-2 papain-like protease inhibit...