Multiple Antitumor Molecular Mechanisms Are Activated by a Fully Synthetic and Stabilized Pharmaceutical Product Delivering the Active Compound Sulforaphane (SFX-01) in Preclinical Model of Human Glioblastoma

• Main Authors: Alessandro Colapietro (Author), Alessandra Rossetti (Author), Andrea Mancini (Author), Stefano Martellucci (Author), Giuseppe Ocone (Author), Fanny Pulcini (Author), Leda Biordi (Author), Loredana Cristiano (Author), Vincenzo Mattei (Author), Simona Delle Monache (Author), Francesco Marampon (Author), Giovanni Luca Gravina (Author), Claudio Festuccia (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Frequent relapses and therapeutic resistance make the management of glioblastoma (GBM, grade IV glioma), extremely difficult. Therefore, it is necessary to develop new pharmacological compounds to be used as a single treatment or in combination with current therapies in order to improve their effect...