Regulation of IFN-γ-mediated PD-L1 expression by MYC in colorectal cancer with wild-type KRAS and TP53 and its clinical implications

• Asıl Yazarlar: Libin Guo (Yazar), Xiaoqiong Tang (Yazar), Sin Wa Wong (Yazar), Anyuan Guo (Yazar), Yao Lin (Yazar), Hang Fai Kwok (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Introduction: In the tumor microenvironment, interferon gamma (IFN-γ) secreted by tumor infiltrating lymphocytes can upregulate programmed cell death 1 ligand 1 (PD-L1) expression in many cancers. The present study evaluated the expression of PD-L1 in selected colorectal cancer cell lines with IFN-γ...