Levofloxacin cures experimental pneumonic plague in African green monkeys.

• Main Authors: Robert Colby Layton (Author), William Mega (Author), Jacob D McDonald (Author), Trevor L Brasel (Author), Edward B Barr (Author), Andrew P Gigliotti (Author), Frederick Koster (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Yersinia pestis, the agent of plague, is considered a potential bioweapon due to rapid lethality when delivered as an aerosol. Levofloxacin was tested for primary pneumonic plague treatment in a nonhuman primate model mimicking human disease. METHODS AND RESULTS: Twenty-four African Gree...