Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease

• Main Authors: Mohammad Zarei (Author), Emma Barroso (Author), Xavier Palomer (Author), Jianli Dai (Author), Patricia Rada (Author), Tania Quesada-López (Author), Joan Carles Escolà-Gil (Author), Lidia Cedó (Author), Mohammad Reza Zali (Author), Mahsa Molaei (Author), Reza Dabiri (Author), Santiago Vázquez (Author), Eugènia Pujol (Author), Ángela M. Valverde (Author), Francesc Villarroya (Author), Yong Liu (Author), Walter Wahli (Author), Manuel Vázquez-Carrera (Author)
• Format: Book
• Published: Elsevier, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The very low-density lipoprotein receptor (VLDLR) plays an important role in the development of hepatic steatosis. In this study, we investigated the role of Peroxisome Proliferator-Activated Receptor (PPAR)β/δ and fibroblast growth factor 21 (FGF21) in hepatic VLDLR regulation. Methods:...