Population pharmacokinetics in critically ill neonates and infants undergoing extracorporeal membrane oxygenation: a literature review

• मुख्य लेखकों: Karel Allegaert (लेखक), Nadir Yalcin (लेखक), Nursel Sürmelioğlu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMJ Publishing Group, 2022-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Extracorporeal membrane oxygenation (ECMO) increases circulating blood volume, causes capillary leak and temporarily alters kidney function. Consequently, pharmacokinetics (PK) can be affected. When applied to neonates and infants, additional dose adjustments are a major concern, as the volume of di...