High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis
Cellular senescence is an irreversible cell growth arrest and is associated with aging and age-related diseases. High plasma phosphate (Pi) and deficiency of Klotho contribute to aging and kidney fibrosis, a pathological feature in the aging kidney and chronic kidney disease. This study examined the...
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Main Authors: | Jenny Maique (Author), Brianna Flores (Author), Mingjun Shi (Author), Sierra Shepard (Author), Zhiyong Zhou (Author), Shirely Yan (Author), Orson W. Moe (Author), Ming Chang Hu (Author) |
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Format: | Book |
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Frontiers Media S.A.,
2020-08-01T00:00:00Z.
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