Oral Absorption of Middle-to-Large Molecules and Its Improvement, with a Focus on New Modality Drugs

• Egile Nagusiak: Daigo Asano (Egilea), Hideo Takakusa (Egilea), Daisuke Nakai (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-12-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

To meet unmet medical needs, middle-to-large molecules, including peptides and oligonucleotides, have emerged as new therapeutic modalities. Owing to their middle-to-large molecular sizes, middle-to-large molecules are not suitable for oral absorption, but there are high expectations around orally b...