Association between the response to B cell depletion therapy and the allele*2 of the HS1,2A enhancer in seropositive rheumatoid arthritis patients Association between the response to B cell depletion therapy and the allele*2 of the HS1,2A enhancer in seropositive rheumatoid arthritis patients

• Main Authors: D. Frezza (Author), B. Tolusso (Author), E. Serone (Author), M.C. Totaro (Author), S. Canestri (Author), E. Gremese (Author), G. Ferraccioli (Author)
• Format: Book
• Published: PAGEPress Publications, 2012-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<em>Objective</em>. Several studies underline the relevance of the genetic background for the response to therapy. We evaluated the relationship between the polymorphism of the HS1,2A enhancer, located in the 3' regulatory region of the heavy immunoglobulin chain (IgH), and the resp...