Knockout of Sema4D alleviates liver fibrosis by suppressing AOX1 expression

• Main Authors: Lifu Wang (Author), Dinghao Li (Author), Zifeng Zhu (Author), Yao Liao (Author), Ji Wu (Author), Yuheng Liu (Author), Ruibing Yang (Author), Hanqiao Dai (Author), Zhongdao Wu (Author), Xi Sun (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Liver fibrosis can occur in many chronic liver diseases, and no effective treatments are available due to the poorly characterized molecular pathogenesis. Semaphorin 4D (Sema4D) has immune functions and serves important roles in T cell priming. Here, we found that Sema4D was highly expressed in fibr...