Palmitoylethanolamide/Baicalein Regulates the Androgen Receptor Signaling and NF-κB/Nrf2 Pathways in Benign Prostatic Hyperplasia

• Main Authors: Ramona D'Amico (Author), Tiziana Genovese (Author), Marika Cordaro (Author), Rosalba Siracusa (Author), Enrico Gugliandolo (Author), Alessio Filippo Peritore (Author), Livia Interdonato (Author), Rosalia Crupi (Author), Salvatore Cuzzocrea (Author), Rosanna Di Paola (Author), Roberta Fusco (Author), Daniela Impellizzeri (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Benign prostatic hyperplasia (BPH) is the most common benign tumor in males. Androgen/androgen receptor (AR) signaling plays a key role in the development of BPH; its alterations cause an imbalance between prostate cell growth and apoptosis. Furthermore, chronic inflammation and oxidative stress, wh...