How can immunohistochemistry improve the diagnosis of pemphigus foliaceus?

• Main Authors: Denise Miyamoto (Author), Celina Maruta (Author), Claudia Santi (Author), Pablo Zoroquiain (Author), Ana Beatriz Dias (Author), Ligia Fukumori (Author), Alexandre Perigo (Author), Valeria Aoki (Author), Miguel Burnier, Jr (Author)
• Format: Book
• Published: Elsevier, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Pemphigus foliaceus (PF) is a rare, autoimmune blistering disorder characterized by the production of autoantibodies against desmoglein 1. The mainstay for diagnosis is the demonstration of immune complex deposition by direct immunofluorescence (DIF) in fresh tissue samples. Immunohistochem...